The forces linked to the new leaders of Syria are engaged in heavy battles with fighters loyal to the president filed Bashar al-Assad in a coastal area of the country.
This is the worst violence in Syria since the rebels overthrew Assad in December and installed an Islamist transitional government.
A war surveillance group, the Syrian Observatory based for British human rights, said that more than 70 people had been killed.
A curfew was imposed in the port cities of Latakia and Ivière, where the fights broke out.
The clashes began when government forces were taken in ambush during a Lataki security operation.
Reinforcements have been sent and videos published online show heavy shots in certain places.
The coastal region is the heart of the Alawite minority and a bastion of the Assad family.
Estimates in the number of people killed in violence vary, and the BBC has not been able to check them independently.
Late Thursday, the Step news agency based in Syrian reported that the forces aligned by the government had killed “around 70” regime veterans, while more than 25 others were captured in Jableh and its surroundings.
There have also been confrontation reports in the cities of Homs and Aleppo.
The crackling of heavy shots in the residential streets in Homs could Be heard on undeclared videos on social networks.
Syrian defense ministry spokesperson, Colonel Hassan Abdul Ghani, warned the Loyalists of Assad Fighting in Latakie via the state media.
“Thousands of people have chosen to give up their weapons and return to their families, while some people insist on fleeing and dying to defend murderers and criminals. The choice is clear: putting your weapons or faced with your inevitable destiny,” he said.
The region has become a major security challenge for acting president Ahmed al-Sharaa.
Alawite activists have said that their community had been subject to violence and attacks since the fall of Assad, especially in rural homs and latakies.
He also faces resistance in the south, where there have been clashes with the forces of Druze in recent days.
Earlier this week, The Minister of Foreign Affairs of Syria has told the global weapons guard dog that the new government was determined to destroy any stock of stocks remaining under-associated.
The government of Assad denied having used chemical weapons during the 14 -year civil war, but activists accused him of having carried out dozens of chemical attacks.